Revolution Medicines shares promising data around KRAS drug combination
Revolution Medicines has released promising Phase 1/2 clinical data for a KRAS drug combination targeting metastatic pancreatic cancer.
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The brief
Revolution Medicines presented clinical data at the ESMO Gastrointestinal Cancers Congress 2026. The data concerns the use of Zoldonrasib combination regimens, specifically the pairing of Zoldonrasib and Daraxonrasib, for patients with RAS G12D metastatic pancreatic cancer in 2nd and 3rd line settings.
Coverage from Yahoo Finance, Endpoints News, and Oncodaily emphasizes the promising nature of the data. Medscape characterizes the findings as practice-changing for GI oncology, while WSAW reports that the experimental drug provides time and hope for patients.
Future developments involve the application of these combination regimens in metastatic pancreatic cancer treatment as the results from the Phase 1/2 trials are further analyzed.
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Quick answers
What specific drug combination was tested?
The combination consists of Zoldonrasib and Daraxonrasib.
Which patient group does this data target?
Patients with RAS G12D metastatic pancreatic cancer in 2nd and 3rd line settings.
Where was this data presented?
The findings were presented at the ESMO Gastrointestinal Cancers Congress 2026.
Coverage (5)
- Anirban Maitra։ Data on Zoldonrasib Plus Daraxonrasib in 2nd and 3rd Line Metastatic Pancreatic Cancer Oncodaily · 2d ago
- Practice-Changing Data in GI Oncology Medscape · 2d ago
- Revolution Medicines Presents Phase 1/2 Clinical Data for Zoldonrasib Combination Regimens in Patients with RAS G12D Metastatic Pancreatic Cancer at ESMO Gastrointestinal Cancers Congress 2026 Yahoo Finance · 2d ago
- Experimental cancer drug brings time and hope for patients WSAW · 2d ago
- Revolution Medicines shares promising data around KRAS drug combination Endpoints News · 2d ago
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